N-Desethyl Sunitinib | VEGFR/PDGFR inhibitor | Probechem Biochemicals

Chemical Structure : N-Desethyl Sunitinib

CAS No.: 356068-97-8

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N-Desethyl Sunitinib (SU11662, SU-11662)

货号: PC-42725Not For Human Use, Lab Use Only.

N-Desethyl Sunitinib is the active metabolite of sunitinib, which is an oral, small-molecule, multi-targeted RTKs inhibitor, sunitinib is a potent, ATP-competitive VEGFR, PDGFRβ and KIT inhibitor.

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10 mg	￥1480	In stock
25 mg	￥2580	In stock
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生物&药学活性

N-Desethyl Sunitinib is the active metabolite of sunitinib, which is an oral, small-molecule, multi-targeted RTKs inhibitor, sunitinib is a potent, ATP-competitive VEGFR, PDGFRβ and KIT inhibitor.

物理化学性质&存储条件

分子量	370.4206
分子式	C20H23FN4O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1H-Pyrrole-3-carboxamide, N-[2-(ethylamino)ethyl]-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-

参考文献

1. Chen X, et al. Biomed Chromatogr. 2015 May;29(5):679-88.

2. Lankheet NA, et al. Br J Cancer. 2014 May 13;110(10):2441-9.

3. Tang SC, et al. J Pharmacol Exp Ther. 2012 Apr;341(1):164-73.

N-Desethyl Sunitinib (SU11662, SU-11662)

生物&药学活性

物理化学性质&存储条件

参考文献

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N-Desethyl Sunitinib (SU11662, SU-11662)

生物&药学活性

物理化学性质&存储条件

参考文献

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