Myricoside

Chemical Structure : Myricoside

CAS No.: 76076-04-5

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货号: PC-26819Not For Human Use, Lab Use Only.

Myricoside is a phenylethanoid triglycoside from Phlomis oppositiflora and small molecule β‑1,4‑galactosyltransferase III (B4GALT3) inhibitor.

规格	价格	库存
5 mg	￥1280	In stock
10 mg	￥1980	In stock
25 mg	￥3480	In stock
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

Myricoside is a phenylethanoid triglycoside from Phlomis oppositiflora and small molecule β‑1,4‑galactosyltransferase III (B4GALT3) inhibitor.
Myricoside occupies the catalytic pocket of B4GALT3, forming hydrogen bonds with key residues (Asp195, Asp197, His291, Asp294) and hydrophobic interactions.
Myricoside induced dose-dependent RB cell death, reduced fibronectin adhesion, decreased β1-integrin galactosylation, and suppressed the FAK–PI3K–AKT–Bcl2 axis, mimicking the effects of B4GALT3 knockdown.
Myricoside attenuated proptosis and corneal neovascularization, and significantly reduced tumor size and invasiveness in orthotopic retinoblastoma xenograft model.

物理化学性质&存储条件

分子量	756.71
分子式	C34H44O19
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(2R,3R,4R,5R,6R)-4-(((2S,3R,4R,5S,6S)-4-(((2S,3R,4R)-3,4-Dihydroxy-4-(hydroxymethyl)tetrahydrofuran-2-yl)oxy)-3,5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6-(3,4-dihydroxyphenethoxy)-5-hydroxy-2-(hydroxymethyl)tetrahydro-2H-pyran-3-yl (E)-3-(3,4-dihydroxyphenyl)acrylate

参考文献

1. Tang J, et al. Cell Death Dis. 2026 Mar 23;17(1):336.

2. Caliş I, et al. Nat Prod Res. 2005 Jul;19(5):493-501.

Myricoside

生物&药学活性

物理化学性质&存储条件

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Myricoside

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