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Myricetin

Chemical Structure : Myricetin

CAS No.: 529-44-2

Myricetin (Cannabiscetin, Myricetol, Myricitin)

货号: PC-72237Not For Human Use, Lab Use Only.

Myricetin (Myricetol, Myricitin) is a flavonoid compound with antioxidant properties, inhibits ENPP1 enzymatic activity with IC50 of 4.8 uM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Myricetin (Myricetol, Myricitin) is a flavonoid compound with antioxidant properties, inhibits ENPP1 enzymatic activity with IC50 of 4.8 uM.
Myricetin demonstrate significant improvement in heart function after injury in treated animal models.
Myricetin exhibited selective inhibition of cell growth (IC50 114.75 uM) and induced apoptosis in MDA-MB-231 cells.
Myricetin act as potential inhibitors of key tumorigenic signaling pathways, such as PI3K/Akt/mTOR, p38 MAPK and NF-κB. decrease the intracellular levels of ROS and pro-inflammatory cytokines, such as TNF-α, IL-1β and IL-6.

物理化学性质&存储条件

分子量 318.237
分子式 C15H10O8
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3,5,7-Trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-1-benzopyran-4-one

参考文献

1. Shen Li, et al. J Clin Invest. 2022 Jan 18;132(2):e149711.

2. Sousa C, et al. Nutr Cancer. 2021 Nov 5:1-15.

3. Vukovic NL, et al. Food Res Int. 2018 Apr;106:71-80.

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