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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Bacterial-Mycobacidin
Mycobacidin

Chemical Structure : Mycobacidin

CAS No.: 539-35-5

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Mycobacidin (Actithiazic acid, Acidomycin)

货号: PC-25838Not For Human Use, Lab Use Only.

Mycobacidin (Acidomycin, Actithiazic acid) is a promising antitubercular activity against a series of contemporary drug susceptible and drug-resistant M. tuberculosis strains with MICs of 0.096-6.2 uM, inhibits biotin synthesis with a Ki of approximately 1 μM through the competitive inhibition of biotin synthase (BioB).

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

Mycobacidin (Acidomycin, Actithiazic acid) is a promising antitubercular activity against a series of contemporary drug susceptible and drug-resistant M. tuberculosis strains with MICs of 0.096-6.2 uM, inhibits biotin synthesis with a Ki of approximately 1 μM through the competitive inhibition of biotin synthase (BioB).

物理化学性质&存储条件

分子量 217.28
分子式 C9H15NO3S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

6-(4-Oxothiazolidin-2-yl)hexanoic acid

参考文献

1. Bockman MR, et al. ACS Infect Dis. 2019 Apr 12;5(4):598-617.

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