Mps1 inhibitor G17

Chemical Structure : Mps1 inhibitor G17

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货号: PC-27877Not For Human Use, Lab Use Only.

Mps1 inhibitor G17 is a selective inhibitor of monopolar spindle 1 (Mps1) with IC50 of 75.5 nM, >30-fold selectivity over TLK1, disrupts spindle assembly checkpoint (SAC) signaling in glioblastoma.

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

Mps1 inhibitor G17 is a selective inhibitor of monopolar spindle 1 (Mps1) with IC50 of 75.5 nM, >30-fold selectivity over TLK1, disrupts spindle assembly checkpoint (SAC) signaling in glioblastoma.

物理化学性质&存储条件

分子量	557.72
分子式	C30H35N7O2S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(1r,4r)-4-((2-((10-(2-morpholinoethyl)-10H-phenothiazin-2-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)cyclohexan-1-ol

参考文献

1. Rai G, et al. J Biol Chem. 2026 Aug 25:113487.