MprB-IN-1 | Mtb MprB inhibitor | Probechem Biochemicals

Chemical Structure : MprB-IN-1

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MprB-IN-1 (Compound 7a)

货号: PC-28698Not For Human Use, Lab Use Only.

MprB-IN-1 (Compound 7a) is a small molecule inhibitor of Mycobacterium tuberculosis (Mtb) histidine kinase MprB, reduces ESX-1-dependent pathogenicity, prevents dissemination of Mtb from the lung to the spleen in mouse model of acute TB infection.

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生物&药学活性

MprB-IN-1 (Compound 7a) is a small molecule inhibitor of Mycobacterium tuberculosis (Mtb) histidine kinase MprB, reduces ESX-1-dependent pathogenicity, prevents dissemination of Mtb from the lung to the spleen in mouse model of acute TB infection.

物理化学性质&存储条件

分子量	398.48
分子式	C21H22N2O4S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	ethyl 2-benzamido-7-((dimethylamino)methyl)-6-hydroxybenzo[b]thiophene-3-carboxylate

参考文献

1. Lobanov V, et al. J Med Chem. 2026 Oct 22;69(20):23968-23990.

MprB-IN-1 (Compound 7a)

生物&药学活性

物理化学性质&存储条件

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MprB-IN-1 (Compound 7a)

生物&药学活性

物理化学性质&存储条件

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