Monophosphoryl lipid A | TLR4 agonist | Probechem Biochemicals

Chemical Structure : Monophosphoryl lipid A

CAS No.: 1246298-63-4

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Monophosphoryl lipid A (MPLA, Glucopyranosyl lipid A)

货号: PC-28403Not For Human Use, Lab Use Only.

Monophosphoryl lipid A (MPLA) is a nontoxic derivative of lipopolysaccharide (LPS) and TRIF-biased toll-like receptor 4 (TLR4) agonist, enhances vaccine adjuvant effects and promotes Th1-type immune response and immunostimulatory properties.

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250 ug	￥2480	In stock
1 mg	￥5480	In stock
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5 mg		Get quote

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分子量	1763.47
分子式	C96H184N3O22P
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	Ammonium (2R,3S,4R,5R,6R)-6-(((2R,3S,4R,5R,6S)-3,6-dihydroxy-5-((R)-3-hydroxytetradecanamido)-4-(((R)-3-hydroxytetradecanoyl)oxy)tetrahydro-2H-pyran-2-yl)methoxy)-2-(hydroxymethyl)-5-((R)-3-(tetradecanoyloxy)tetradecanamido)-4-(((R)-3-(tetradecanoyloxy)tetradecanoyl)oxy)tetrahydro-2H-pyran-3-yl hydrogen phosphate

参考文献

1. Tiberio L, et al. Vaccine. 2004 Mar 29;22(11-12):1515-23.

2. Bevaart L, et al. Cancer Res. 2006 Feb 1;66(3):1261-4.

3. Cekic C, et al. J Biol Chem. 2009 Nov 13;284(46):31982-91.

4. Mata-Haro V, et al. Science. 2007 Jun 15;316(5831):1628-32.

Monophosphoryl lipid A (MPLA, Glucopyranosyl lipid A)

生物&药学活性

物理化学性质&存储条件

参考文献

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Monophosphoryl lipid A (MPLA, Glucopyranosyl lipid A)

生物&药学活性

物理化学性质&存储条件

参考文献

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