MitoBloCK-11 | Mitochondrial protein import inhibitor

Chemical Structure : MitoBloCK-11

CAS No.: 413606-16-3

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MitoBloCK-11 (MB-11, MitoBloCK 11)

货号: PC-35923Not For Human Use, Lab Use Only.

MitoBloCK-11 (MB-11) is a s mall molecule inhibitor of mitochondrial protein import possibly acts through transport protein Seo1, but not Tom70 or Tom20.

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5 mg	￥2580	In stock
10 mg	￥4280	In stock
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生物&药学活性

MitoBloCK-11 (MB-11) is a s mall molecule inhibitor of mitochondrial protein import possibly acts through transport protein Seo1, but not Tom70 or Tom20.
MitoBloCK-11 inhibits precursor proteins that contain hydrophobic segments, confers growth in media lacking uracil in a specific manner and affects zebrafish development.

物理化学性质&存储条件

分子量	434.264
分子式	C17H12BrN3O4S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-((4-bromonaphthalen-1-yl)oxy)-N'-((5-nitrothiophen-2-yl)methylene)acetohydrazide

参考文献

1. Conti, M. (2018). Small Molecule Probes of Mitochondrial Translocases Elucidate PINK1 Trafficking in PINK1/Parkin Regulated Mitophagy. UCLA.

2. Miyata N, et al. J Biol Chem. 2017 Mar 31;292(13):5429-5442.

MitoBloCK-11 (MB-11, MitoBloCK 11)

生物&药学活性

物理化学性质&存储条件

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MitoBloCK-11 (MB-11, MitoBloCK 11)

生物&药学活性

物理化学性质&存储条件

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