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Mito-C

Chemical Structure : Mito-C

CAS No.: 2371004-96-3

Mito-C

货号: PC-73358Not For Human Use, Lab Use Only.

Mito-C is a specific chemical compound targeting NEETs proteins, induces mitochondrial network fragmentation and represses dengue viral replication.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    Mito-C is a specific chemical compound targeting NEETs proteins, induces mitochondrial network fragmentation and represses dengue viral replication.
    Mito-C modifies mitochondrial morphology and dynamics by stabilizing ER‐Mitochondria contact sites (ER‐MTcs).
    Mito-C is able to counteract dengue virus‐induced mitochondria network hyperfusion and to strongly reduce Dengue virus replication, but not HBV replication cycle.
    MITO‐C shows impact on NAF1 levels and subcellular localization.
    Mito‐C causes DRP1‐dependent mitochondrial fission and ER‐mitochondria contact‐sites increase.
    Mito‐C possesses in vitro anti‐viral properties specifically against viruses that enhance mitochondrial fusion as a necessary part of their replication cycle.

    物理化学性质&存储条件

    分子量 389.466
    分子式 C20H23NO5S
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    2-(3,4-dimethoxybenzamido)-6,6-dimethyl-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid

    参考文献

    1. Diana Molino, et al. EMBO Rep. 2020 Dec 3;21(12):e49019.

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