Minocycline

Chemical Structure : Minocycline

CAS No.:

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货号: PC-28610Not For Human Use, Lab Use Only.

Minocycline is a tetracycline antibiotic with neuroprotective, antiapoptotic, anti-inflammatory and antimicrobial effects, inhibits bacterial protein synthesis through binding with the 30S subunit of the bacterial ribosome, also is a hypoxia-inducible factor (HIF)-1α inhibitor.

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生物&药学活性

物理化学性质&存储条件

分子量	457.48
分子式	C23H27N3O7
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(4S,4aS,5aR,12aS)-4,7-Bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide

参考文献

1. Hu X, et al. Eur J Pharmacol. 2011 Mar 11;654(3):274-9.

2. Padi SS, et al. Eur J Pharmacol. 2008 Dec 28;601(1-3):79-87.

3. Venniyoor A, et al. Front Oncol. 2016 Oct 27;6:231.

Minocycline

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Minocycline

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