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Miltefosine

Chemical Structure : Miltefosine

CAS No.: 58066-85-6

Miltefosine (Hexadecyl phosphocholine, HePC)

货号: PC-23591Not For Human Use, Lab Use Only.

Miltefosine is a phosphatidylcholine analog with anti-leishmanial activity, inhibits PI3K/Akt activity, shows broad spectrum antimicrobial, anti-leishmanial and anticoronaviral activity.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Miltefosine is a phosphatidylcholine analog with anti-leishmanial activity, inhibits PI3K/Akt activity, shows broad spectrum antimicrobial, anti-leishmanial and anticoronaviral activity.
Miltefosine is an antiprotozoal prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of leishmaniasis.
Miltefosine shows broad spectrum antimicrobial, anti-leishmanial.
Miltefosine has a role as an antineoplastic agent, an antiprotozoal drug, an antifungal agent, an immunomodulator, an anti-inflammatory agent, an apoptosis inducer, a protein kinase inhibitor and an anticoronaviral agent.

物理化学性质&存储条件

分子量 407.58
分子式 C21H46NO4P
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Hexadecyl (2-(trimethylammonio)ethyl) phosphate

参考文献

1. Uberall F, et al.Cancer Res. 1991 Feb 1;51(3):807-12.

2. Bhatt AP, et al. Blood. 2010 Jun 3;115(22):4455-63.

3. Chugh P, et al. 2008 Jan 31;5:11

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