Miglustat hydrochloride |CAS:210110-90-0 Probechem Biochemicals

Chemical Structure : Miglustat hydrochloride

CAS No.: 210110-90-0

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Miglustat hydrochloride (NB-DNJ hydrochloride, OGT-918 hydrochloride)

货号: PC-45142Not For Human Use, Lab Use Only.

Miglustat hydrochloride (N-Butyldeoxynojirimycin, SC-48334, NB-DNJ, OGT-918) is an orally active and reversible inhibitor of glucosylceramide synthase (GCS, ceramide glucosyltransferase).

规格	价格	库存
5 mg	￥780	In stock
10 mg	￥1180	In stock
25 mg	￥2180	In stock
50 mg	￥3580	In stock
100 mg		Get quote

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生物&药学活性

Miglustat hydrochloride (N-Butyldeoxynojirimycin, SC-48334, NB-DNJ, OGT-918) is an orally active and reversible inhibitor of glucosylceramide synthase (GCS, ceramide glucosyltransferase).
Miglustat inhibits glycolipid biosynthesis, has no effect on the maturation of N-linked oligosaccharides or on lysosomal glucocerebrosidase.
Miglustat is used primarily to treat type I Gaucher disease (GD1).

物理化学性质&存储条件

分子量	255.739
分子式	C10H22ClNO4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	H2O: ≥ 34 mg/mL
Chemical Name/SMILES	3,4,5-Piperidinetriol, 1-butyl-2-(hydroxymethyl)-, hydrochloride (1:1), (2R,3R,4R,5S)-

参考文献

1. Platt FM, et al. J Biol Chem. 1994 Oct 28;269(43):27108-14.

2. D'Arcangelo G, et al. Neural Plast. 2016;2016:3830424.

3. Fischer PB, et al. J Virol. 1995 Sep;69(9):5791-7.

Miglustat hydrochloride (NB-DNJ hydrochloride, OGT-918 hydrochloride)

生物&药学活性

物理化学性质&存储条件

参考文献

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Miglustat hydrochloride (NB-DNJ hydrochloride, OGT-918 hydrochloride)

生物&药学活性

物理化学性质&存储条件

参考文献

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