iMDK | Midkine inhibitor | Probechem Biochemicals

Chemical Structure : Midkine inhibitor (iMDK)

CAS No.: 881970-80-5

加入收藏

Midkine inhibitor (iMDK) (Inhibitor of Midkine)

货号: PC-61962Not For Human Use, Lab Use Only.

Midkine inhibitor (iMDK) is a small molecule inhibitor of the growth factor Midkine (MDK) that suppresses the endogenous expression of MDK but not other growth factors such as PTN or VEGF.

规格	价格	库存
5 mg	￥1380	In stock
10 mg	￥2280	In stock
25 mg	￥3780	In stock
50 mg		Get quote
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

Midkine inhibitor (iMDK) is a small molecule inhibitor of the growth factor Midkine (MDK) that suppresses the endogenous expression of MDK but not other growth factors such as PTN or VEGF.
Midkine inhibitor (iMDK) inhibits the cell growth of MDK-positive H441 lung adenocarcinoma cells that harbor an oncogenic KRAS mutation and H520 squamous cell lung cancer cells, inhibits PI3K pathway and induces apoptosis.
Midkine inhibitor (iMDK) significantly inhibits tumor growth in a xenograft mouse model in vivo.

物理化学性质&存储条件

分子量	376.4
分子式	C21H13FN2O2S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-[2-[(4-Fluorophenyl)methyl]imidazo[2,1-b]thiazol-6-yl]-2H-1-benzopyran-2-one

参考文献

1. Hao H, et al. PLoS One. 2013 Aug 16;8(8):e71093.

2. Ishida N, et al. Exp Cell Res. 2015 Jul 15;335(2):197-206.

3. Masui M, et al. Anticancer Res. 2016 Jun;36(6):2775-81.

Midkine inhibitor (iMDK) (Inhibitor of Midkine)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Midkine inhibitor (iMDK) (Inhibitor of Midkine)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.