Metyrapone (Su-4885, NSC-25265) | 11β-hydroxylase inhibitor

Chemical Structure : Metyrapone

CAS No.: 54-36-4

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Metyrapone (NSC 25265, Su-4885)

货号: PC-28058Not For Human Use, Lab Use Only.

Metyrapone (Su-4885, NSC-25265) is a potent and orally active 11β-hydroxylase (CYP11B1) inhibitor and autophagy activator, also inhibits the production of aldosterone, inhibits synthesis of endogenous adrenal corticosteroid, decreases glucocorticoid levels, and also affects behavior and emotion in vivo.

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500 mg	￥480	In stock
1 g	￥780	In stock
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生物&药学活性

Metyrapone (Su-4885, NSC-25265) is a potent and orally active 11β-hydroxylase (CYP11B1) inhibitor and autophagy activator, also inhibits the production of aldosterone, inhibits synthesis of endogenous adrenal corticosteroid, decreases glucocorticoid levels, and also affects behavior and emotion in vivo.

物理化学性质&存储条件

分子量	226.28
分子式	C14H14N2O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-Methyl-1,2-di(pyridin-3-yl)propan-1-one

参考文献

1. Roozendaal B, et al. Psychoneuroendocrinology. 1996 Nov;21(8):681-93.

2. CLEVELAND WW, et al. J Clin Endocrinol Metab. 1962 Mar;22:281-6.

3. Napoli JL, et al. J Med Chem. 1977 Jun;20(6):762-6.

Metyrapone (NSC 25265, Su-4885)

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物理化学性质&存储条件

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Metyrapone (NSC 25265, Su-4885)

生物&药学活性

物理化学性质&存储条件

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