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首页-小分子抑制剂&激动剂-GPCR-Dopamine Receptor-Metoclopramide hydrochloride hydrate
Metoclopramide hydrochloride hydrate

Chemical Structure : Metoclopramide hydrochloride hydrate

CAS No.: 54143-57-6

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Metoclopramide hydrochloride hydrate

货号: PC-45205Not For Human Use, Lab Use Only.

A potent dopamine D2 receptor antagonist with Ki of 28 nM.

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500 mg ￥960 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

A potent dopamine D2 receptor antagonist with Ki of 28 nM; also is a mixed 5-HT3 receptor antagonist/5-HT4 receptor agonist; commonly used to treat nausea and vomiting caused by chemotherapy.

Chemotherapeutic Agents

Phase 2 Discontinued

物理化学性质&存储条件

分子量 354.2726
分子式 C14H25Cl2N3O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

Benzamide, 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxy-, hydrochloride, hydrate (1:1:1)

参考文献

1. Matsui A, et al. J Pharmacol Exp Ther. 1998 Nov;287(2):725-32.

2. Tonini M, et al. Pharmacol Res. 1995 May;31(5):257-60.

3. Bateman DN, et al. Br J Clin Pharmacol. 1978 Nov;6(5):401-7.

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