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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Filovirus-Methylene Blue
Methylene Blue

Chemical Structure : Methylene Blue

CAS No.: 61-73-4

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Methylene Blue (Basic Blue 9, CI-52015, Methylthioninium chloride)

货号: PC-23175Not For Human Use, Lab Use Only.

Methylene blue (Basic Blue 9) is a guanylyl cyclase (sGC), monoamine oxidase A (MAO-A) and NO synthase (NOS) inhibitor, also is a Tau aggregation inhibitor, inhibits DENV NS2B-NS3 inhibitor (IC50=9 µM) and DENV infection in cells in the submicromolar range (EC50=0.36 µM).

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100 mg ￥580 In stock
500 mg ￥980 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Methylene blue (Basic Blue 9) is a guanylyl cyclase (sGC), monoamine oxidase A (MAO-A) and NO synthase (NOS) inhibitor, also is a Tau aggregation inhibitor, inhibits DENV NS2B-NS3 inhibitor (IC50=9 µM) and DENV infection in cells in the submicromolar range (EC50=0.36 µM).

物理化学性质&存储条件

分子量 319.85
分子式 C16H18ClN3S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

3,7-Bis(dimethylamino)phenothiazin-5-ium chloride

参考文献

1. Lorenzo Cavina, et al. Molecules. 2024 Aug 27;29(17):4047.

2. Klamer D, et, al. Basic Clin Pharmacol Toxicol. 2004 Feb;94(2):65-72.

3. Fenn AM, et, al. J Neurotrauma. 2015 Jan 15;32(2):127-38.

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