Methyl-β-cyclodextrin |CAS:128446-36-6 Probechem Biochemicals

Chemical Structure : Methyl-β-cyclodextrin

CAS No.: 128446-36-6

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Methyl-β-cyclodextrin (Methyl-beta-cyclodextrin;MβCD)

货号: PC-42392Not For Human Use, Lab Use Only.

A cholesterol depleting agent that shows antitumor activity both in vitro and in vivo.

规格	价格	库存
5 g	￥560	In stock
10 g	￥800	In stock
25 g	￥1520	In stock
50 g	￥1920	In stock

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生物&药学活性

A cholesterol depleting agent that shows antitumor activity both in vitro and in vivo; induces caspase-dependent apoptosis in PEL cells via cholesterol depletion from the plasma membrane; significantly potentiates the activity of doxorubicin used alone on both sensitive and multidrug-resistant cell lines, and enhances the susceptibility of human breast cancer cells to carboplatin and 5-FU.

物理化学性质&存储条件

分子量	N/A
分子式	1310 (Average)
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	DMSO: ≥ 31 mg/mL
Chemical Name/SMILES	β-Cyclodextrin, methyl ethers

参考文献

1. Mahammad S, et al. Methods Mol Biol. 2015;1232:91-102.

2. Gotoh K, et al. Biochem Biophys Res Commun. 2014 Dec 12;455(3-4):285-9.

3. Grosse PY, et al. Cancer Chemother Pharmacol. 1997;40(6):489-94.

4. Upadhyay AK, et al. Toxicol Appl Pharmacol. 2006 Oct 15;216(2):177-85.

Methyl-β-cyclodextrin (Methyl-beta-cyclodextrin;MβCD)

生物&药学活性

物理化学性质&存储条件

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Methyl-β-cyclodextrin (Methyl-beta-cyclodextrin;MβCD)

生物&药学活性

物理化学性质&存储条件

参考文献

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