Metesind glucuronate |CAS:157182-23-5 Probechem Biochemicals

首页-小分子抑制剂&激动剂-Cell Cycle/DNA Damage-Nucleoside Antimetabolite/Analog-Metesind glucuronate

Chemical Structure : Metesind glucuronate

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Metesind glucuronate (AG 331;AG-265 glucuronate)

货号: PC-63014Not For Human Use, Lab Use Only.

Metesind glucuronate (AG 331.

规格	价格	库存	数量
100 mg		Get quote
250 mg		Get quote
500 mg		Get quote
1 g		Get quote

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

Metesind glucuronate (AG 331;AG-265 glucuronate) is a potent thymidylate synthase (TS) inhibitor with IC50/IC90 of 0.7/3.0 uM; inhibits the cofactor binding site of TS, and accumulates in the S phase of the cell cycle in H35 cells at 10 uM.

Brain Cancer

Discontinued

物理化学性质&存储条件

分子量	630.679
分子式	C23H24N4O3SC6.H10O7
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	6-[N-Methyl-N-[4-(morpholinosulfonyl)benzyl]amino]benz[cd]indol-2(1H)-imine glucuronate

参考文献

1. Pressacco J, et al. Cancer Res. 1995 Apr 1;55(7):1505-8.

2. O'Connor BM, et al. Cancer Chemother Pharmacol. 1994;34(3):225-9.

3. Panadero A, et al. Oncol Res. 1995;7(2):73-81.

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Metesind glucuronate (AG 331;AG-265 glucuronate)

生物&药学活性

物理化学性质&存储条件

参考文献

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Metesind glucuronate (AG 331;AG-265 glucuronate)

生物&药学活性

物理化学性质&存储条件

参考文献

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