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首页-小分子抑制剂&激动剂-Apoptosis-Bcl-2-Mesutoclax
Mesutoclax

Chemical Structure : Mesutoclax

CAS No.: 2760536-87-4

Mesutoclax (ICP-248)

货号: PC-25072Not For Human Use, Lab Use Only.

Mesutoclax (ICP-248) is a highly selective and potent, orally active BCL2 inhibitor.

规格 价格 库存 数量
50 mg Get quote
100 mg Get quote
250 mg Get quote

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

Mesutoclax (ICP-248) is a highly selective and potent, orally active BCL2 inhibitor.

物理化学性质&存储条件

分子量 884.45
分子式 C45H50ClN7O8S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Benzamide, 4-[(3R)-4-[[2-(4-chlorophenyl)-4,4-dimethyl-1-cyclohexen-1-yl]methyl]-3-methyl-1-piperazinyl]-N-[[4-[[(2S)-1,4-dioxan-2-ylmethyl]amino]-3-nitrophenyl]sulfonyl]-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)-

参考文献

1. Shuhua YI, et al. Meeting Abstract: 2025 ASCO Annual Meeting I.

2. Patent WO2022028353 A1.

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