Mesotrypsin inhibitor CP13

Chemical Structure : Mesotrypsin inhibitor CP13

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货号: PC-24924Not For Human Use, Lab Use Only.

Mesotrypsin inhibitor CP13 is a selective, small molecule inhibitor of mesotrypsin with Ki of 47 uM, 4-fold selective over human trypsin 1 and trypsin 2.

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生物&药学活性

Mesotrypsin inhibitor CP13 is a selective, small molecule inhibitor of mesotrypsin with Ki of 47 uM, 4-fold selective over human trypsin 1 and trypsin 2.
Mesotrypsin inhibitor CP13 shows limited activity against various trypsin-like plasma serine proteases, including Plasma kallikrein, plasmin, thrombin, and factor Xa.

物理化学性质&存储条件

分子量	300.34
分子式	C14H12N4O2S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(3-hydroxypyridin-2-yl)-4-(2-methylthiazol-4-yl)-1H-pyrrole-2-carboxamide

参考文献

1. Matt Coban, et al. Sci Adv. 2025 Jul 4;11(27):eadu9129.