Mertansine |CAS:139504-50-0 Probechem Biochemicals

Chemical Structure : Mertansine

CAS No.: 139504-50-0

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货号: PC-45714Not For Human Use, Lab Use Only.

Mertansine (DM1) is a tubulin inhibitor.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Mertansine (DM1) is a tubulin inhibitor; thiol-containing maytansinoid that create an antibody-drug conjugate (ADC); an ADC payload.

分子量	738.2877
分子式	C35H48ClN3O10S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	DMSO: ≥ 83.33 mg/mL
Chemical Name/SMILES	Maytansine, N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-

1. Niculescu-Duvaz I. Curr Opin Mol Ther. 2010 Jun;12(3):350-60.

2. Lambert JM. Br J Clin Pharmacol. 2013 Aug;76(2):248-62.

3. Helft PR, et al. Clin Cancer Res. 2004 Jul 1;10(13):4363-8.

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