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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-HCV-Mericitabine
Mericitabine

Chemical Structure : Mericitabine

CAS No.: 940908-79-2

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Mericitabine (RG-7128, R-7128, PSI-6130 diisobutyrate)

货号: PC-42479Not For Human Use, Lab Use Only.

Mericitabine (RG-7128, R-7128, PSI-6130 diisobutyrate) is the prodrug of PSI-6130, a potent, specific inhibitor of HCV RNA synthesis by inhibiting the NS5B RNA polymerase.

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10 mg ￥2280 In stock
25 mg ￥3780 In stock
50 mg ￥5880 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Mericitabine (RG-7128, R-7128, PSI-6130 diisobutyrate) is the prodrug of PSI-6130, a potent, specific inhibitor of HCV RNA synthesis by inhibiting the NS5B RNA polymerase.

物理化学性质&存储条件

分子量 399.4139
分子式 C18H26FN3O6
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

Cytidine, 2'-deoxy-2'-fluoro-2'-methyl-, 3',5'-bis(2-methylpropanoate), (2'R)-

参考文献

1. McCown MF, et al. Antimicrob Agents Chemother. 2008 May;52(5):1604-12.

2. Ali S, et al. Antimicrob Agents Chemother. 2008 Dec;52(12):4356-69.

3. Le Pogam S, et al. J Infect Dis. 2010 Nov 15;202(10):1510-9.

4. Guedj J, et al. Hepatology. 2012 Apr;55(4):1030-7.

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