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首页-小分子抑制剂&激动剂-NF-κB Pathway-NF-κB-Menaquinone-7
Menaquinone-7

Chemical Structure : Menaquinone-7

CAS No.: 2124-57-4

Menaquinone-7 (Vitamin K2-7, Vitamin K2(35), MK-7)

货号: PC-28419Not For Human Use, Lab Use Only.

Menaquinone-7 (Vitamin K2, MK-7) is a highly preferred form of vitamin K2 with antioxidant and anti-inflammatory properties, attenuates RSL3-induced lipid peroxidation, ferroptosis, and NF-κB-dependent inflammatory activation.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Menaquinone-7 (Vitamin K2, MK-7) is a highly preferred form of vitamin K2 with antioxidant and anti-inflammatory properties, attenuates RSL3-induced lipid peroxidation, ferroptosis, and NF-κB-dependent inflammatory activation. Menaquinone-7 inhibits osteoclast bone resorption in vitro and stimulates bone formation in femoral tissue of aged female rats.
Menaquinone-7 is also a pharmacological option for activating Gla matrix protein and intervening in the progression of calcific aortic stenosis (CAVS).
Menaquinone-7 also is a cytoprotective agent in ovarian ischemia-reperfusion.

物理化学性质&存储条件

分子量 649.02
分子式 C46H64O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-((2E,6E,10E,14E,18E,22E)-3,7,11,15,19,23,27-Heptamethyloctacosa-2,6,10,14,18,22,26-heptaen-1-yl)-3-methylnaphthalene-1,4-dione

参考文献

1. Repges E, et al. Sci Rep. 2026 Jun 19;16(1):19171.

2. Ali SK, et al. Tissue Cell. 2026 Oct;102:103571.

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