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首页-抗体药物偶连体和PROTACs-ADCs Linker/Click Chemistry-Mc-Val-Cit-PABC-PNP
Mc-Val-Cit-PABC-PNP

Chemical Structure : Mc-Val-Cit-PABC-PNP

CAS No.: 159857-81-5

Mc-Val-Cit-PABC-PNP (Maleimidocaproyl-L-valine-L-citrulline-p-aminobenzyl alcohol p-nitrophenyl carbonate)

货号: PC-45783Not For Human Use, Lab Use Only.

Mc-Val-Cit-PABC-PNP is a cathepsin cleavable ADC peptide linker for ADC design.

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100 mg ¥580 In stock
250 mg ¥980 In stock
1 g ¥1580 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Mc-Val-Cit-PABC-PNP is a cathepsin cleavable ADC peptide linker for ADC design.

物理化学性质&存储条件

分子量 737.7562
分子式 C35H43N7O11
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: ≥ 37 mg/mL

Chemical Name/SMILES

L-Ornithinamide, N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aminocarbonyl)-N-[4-[[[(4-nitrophenoxy)carbonyl]oxy]methyl]phenyl]-

参考文献

1. Dubowchik GM, et al. Bioconjug Chem. 2002 Jul-Aug;13(4):855-69.

2. Doronina SO, et al. Bioconjug Chem. 2008 Oct;19(10):1960-3.

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