Maribavir | CMV pUL97 inhibitor | Probechem Biochemicals

Chemical Structure : Maribavir

CAS No.: 176161-24-3

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Maribavir (Benzimidavir, 1263W94)

货号: PC-38784Not For Human Use, Lab Use Only.

Maribavir (1263W94, Benzimidavir) is a potent and selective inhibitor of human cytomegalovirus (HCMV) replication with IC50 of 0.13 uM against laboratory strain AD169, and 0.03-0.13 uM against 10 clinical HCMV isolates.

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10 mg	￥2980	In stock
25 mg	￥4980	In stock
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生物&药学活性

Maribavir (1263W94, Benzimidavir) is a potent and selective inhibitor of human cytomegalovirus (HCMV) replication with IC50 of 0.13 uM against laboratory strain AD169, and 0.03-0.13 uM against 10 clinical HCMV isolates.
Maribavir (1263W94) is active against viral mutants that are resistant to GCV, CDV, and PFA.
Maribavir is orally bioavailable, and is the first and only antiviral agent that targets and inhibits the pUL97 protein kinase and its natural substrates.

物理化学性质&存储条件

分子量	376.234
分子式	C15H19Cl2N3O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(2S,3S,4R,5S)-2-(5,6-dichloro-2-(isopropylamino)-1H-benzo[d]imidazol-1-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol

参考文献

1. Koszalka GW, et al. Antimicrob Agents Chemother. 2002 Aug;46(8):2373-80.

2. Gershburg E, et al. J Virol. 2002 Feb;76(3):998-1003.

Maribavir (Benzimidavir, 1263W94)

生物&药学活性

物理化学性质&存储条件

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Maribavir (Benzimidavir, 1263W94)

生物&药学活性

物理化学性质&存储条件

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