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Malic Enzyme inhibitor ME1

Chemical Structure : Malic Enzyme inhibitor ME1

CAS No.: 522649-59-8

Malic Enzyme inhibitor ME1 (ME1)

货号: PC-35817Not For Human Use, Lab Use Only.

Malic Enzyme inhibitor ME1 (ME1) is a small molecule inhibitor of Malic Enzyme (ME1) with IC50 of 0.15 uM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Malic Enzyme inhibitor ME1 (ME1) is a small molecule inhibitor of Malic Enzyme (ME1) with IC50 of 0.15 uM.
ME1 suppresses growth of human CRC cells in vitro, with little effect on normal rat intestinal epithelial cells.

物理化学性质&存储条件

分子量 351.406
分子式 C20H21N3O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-[4-(4-hydroxyphenyl)piperazin-1-yl]-1-phenylpyrrolidine-2,5-dione

参考文献

1. Zhang YJ, et al. Bioorg Med Chem Lett. 2006 Feb;16(3):525-8.

2. Fernandes LM, et al. Sci Rep. 2018 Sep 24;8(1):14268.

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