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首页-小分子抑制剂&激动剂-PI3K/Akt/mTOR Pathway-PI3K-Macamide B
Macamide B

Chemical Structure : Macamide B

CAS No.: 74058-71-2

Macamide B (N-Benzylpalmitamide, N-Benzylhexadecanamide)

货号: PC-28717Not For Human Use, Lab Use Only.

Macamide B is an effective active ingredient of maca, exerts a neuroprotective effect on neonatal hypoxic-ischemic brain damage (HIBD), enhances autophagy through the PI3K/AKT signaling pathway.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Macamide B is an effective active ingredient of maca, exerts a neuroprotective effect on neonatal hypoxic-ischemic brain damage (HIBD), enhances autophagy through the PI3K/AKT signaling pathway.
Macamide B pretreatment significantly decreases brain damage and improves the recovery of neural function after HIBD.
Macamide B pretreatment activates the PI3K/AKT signaling pathway after HIBD, enhances autophagy, and reduces hypoxic-ischemic (HI)-induced apoptosis.
Macamide B reduces HIBD-induced apoptosis and exerts neuroprotective effects on neonatal HIBD.
Macamide B suppresses lung cancer progression potentially via the ATM signaling pathway.

物理化学性质&存储条件

分子量 345.57
分子式 C23H39NO
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-benzylpalmitamide

参考文献

1. Yang X, et et al. Mol Neurobiol. 2022 May;59(5):2776-2798.

2. Tao H, et al. Oncol Lett. 2023 Feb 6;25(3):115.

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