MYLS22 | Opa1 inhibitor | Probechem Biochemicals

Chemical Structure : MYLS22

CAS No.: 306959-01-3

加入收藏

MYLS22 (MYLS 22)

货号: PC-38609Not For Human Use, Lab Use Only.

MYLS22 is a specific, nontoxic small molecule inhibitor of the inner mitochondrial membrane mitochondrial fusion protein optic atrophy 1 (OPA1), curtails tumor growth and metastasisin vitro and in vivo.

规格	价格	库存
10 mg	￥980	In stock
25 mg	￥1580	In stock
50 mg	￥2480	In stock
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

MYLS22 is a specific, nontoxic small molecule inhibitor of the inner mitochondrial membrane mitochondrial fusion protein optic atrophy 1 (OPA1), curtails tumor growth and metastasisin vitro and in vivo.
MYLS22 downregulates the angiogenic factors (FGFR, FGF, EGF, and PDGF) used by tumors escaping from VEGF inhibitors.
MYLS22 (peritumoral injection 10 mg/kg/die) curtailed tumor growth, did not display any additive effect in Opa1+/ΔEC mice.
Pharmacological OPA1 inhibition via MYLS22 reduces breast cancer hallmarks in vitro.

物理化学性质&存储条件

分子量	443.52
分子式	C24H21N5O2S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(2,3-Dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)-3-methyl-1-phenyl-1H-thieno[2,3-c]pyrazole-5-carboxamide

参考文献

1. Herkenne S, et al. Cell Metab. 2020 May 5;31(5):987-1003.e8.

2. Corrado M, et al. Cell Death Differ. 2021 Jul;28(7):2194-2206.

MYLS22 (MYLS 22)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

MYLS22 (MYLS 22)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.