MY10 | PTPRZ1 inhibitor | Probechem Biochemicals

Chemical Structure : MY10

CAS No.: 2204270-73-3

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MY10 (PTPRZ1 inhibitor MY10)

货号: PC-35023Not For Human Use, Lab Use Only.

MY10 is a small-molecule inhibitor of RPTPβ/ζ (PTPRZ1) with IC50 of 0.1 uM, significantly increases the phosphorylation of key tyrosine residues of RPTPβ/ζ substrates involved in neuronal survival and differentiation.

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5 mg	￥1580	In stock
10 mg	￥2480	In stock
25 mg	￥4280	In stock
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100 mg		Get quote

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生物&药学活性

MY10 is a small-molecule inhibitor of RPTPβ/ζ (PTPRZ1) with IC50 of 0.1 uM, significantly increases the phosphorylation of key tyrosine residues of RPTPβ/ζ substrates involved in neuronal survival and differentiation.
MY10 blocks ethanol conditioned place preference, shows limited effects on ethanol-induced ataxia, and potentiates the sedative effects of ethanol in mice.
MY10 increases levels of phosphorylated ALK and TrkA in neuroblastoma cells, modulates signaling pathways activated by alcohol.

物理化学性质&存储条件

分子量	384.354
分子式	C15H10F6OS2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(trifluoromethyl)(4-((4-((trifluoromethyl)thio)benzyl)oxy)phenyl)sulfane

参考文献

1. Fernández-Calle R, et al. Neuropharmacology. 2018 May 9;137:86-95.

MY10 (PTPRZ1 inhibitor MY10)

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物理化学性质&存储条件

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MY10 (PTPRZ1 inhibitor MY10)

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物理化学性质&存储条件

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