Chemical Structure : MV1
CAS No.: 1001600-54-9
货号: PC-70207Not For Human Use, Lab Use Only.
MV1 is a small-molecule IAP antagonist that binds to select baculovirus IAP repeat (BIR) domains resulting in dramatic induction of auto-ubiquitination activity and rapid proteasomal degradation of c-IAPs.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
5 mg | ¥2580 | In stock | |
10 mg | ¥3980 | In stock | |
25 mg | ¥5980 | In stock | |
50 mg | Get quote | ||
100 mg | Get quote |
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MV1 is a small-molecule IAP antagonist that binds to select baculovirus IAP repeat (BIR) domains resulting in dramatic induction of auto-ubiquitination activity and rapid proteasomal degradation of c-IAPs.
MV1 induces cell death that is dependent on TNF signaling and de novo protein biosynthesis.
分子量 | 576.738 | |
分子式 | C33H44N4O5 | |
外观性状 | Solid | |
储存条件 |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
methyl 2-((S)-1-((S)-2-cyclohexyl-2-((S)-2-(methylamino)propanamido)acetyl)pyrrolidine-2-carboxamido)-3,3-diphenylpropanoate |
1. Varfolomeev E, et al. Cell. 2007 Nov 16;131(4):669-81.
2. Shibata N, et al. J Med Chem. 2017 Jun 23. doi: 10.1021/acs.jmedchem.7b00168.
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