Chemical Structure : MTB-9655
CAS No.: 2332820-04-7
货号: PC-23738Not For Human Use, Lab Use Only.
MTB-9655 is a potent, selective and orally bioavailable Acetyl-Coenzyme A Synthetase 2 (ACSS2) inhibitor with biochemical IC50 of 0.15 nM and EC50 of 3 nM in cellular assays.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
5 mg | ¥1280 | In stock | |
10 mg | ¥1980 | In stock | |
25 mg | ¥3480 | In stock | |
50 mg | Get quote | ||
100 mg | Get quote |
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MTB-9655 is a potent, selective and orally bioavailable Acetyl-Coenzyme A Synthetase 2 (ACSS2) inhibitor with biochemical IC50 of 0.15 nM and EC50 of 3 nM in cellular assays.
MTB-9655 induces anti-tumor effects in xenograft mouse models of human colorectal, breast and lung cancers that express high levels of ACSS2.
分子量 | 415.40 | |
分子式 | C21H19F2N3O4 | |
外观性状 | Solid | |
储存条件 |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
Benzoic acid, 3-[4-[[[3-(1,1-difluoroethyl)phenyl]amino]carbonyl]-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl]-, methyl ester |
1. Ruth Perets, et al. Journal of Clinical Oncology Volume 40, Number 16_suppl, 2022 ASCO Annual Meeting I
2. Andreas Goutopoulos, et al.Cancer Res (2022) 82 (12_Supplement): 2326.
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