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首页-小分子抑制剂&激动剂-GPCR-Melatonin Receptor-MT2 antagonist DH97
MT2 antagonist DH97

Chemical Structure : MT2 antagonist DH97

CAS No.: 220339-00-4

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MT2 antagonist DH97

货号: PC-23431Not For Human Use, Lab Use Only.

DH97 is a potent and selective antagonist of MT2 melatonin receptor with pKi value of 8.03 for human MT2 receptor, shows 89- and 229-fold selectivity over human MT1 and Xenopus mel1c receptor subtypes.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

DH97 is a potent and selective antagonist of MT2 melatonin receptor with pKi value of 8.03 for human MT2 receptor, shows 89- and 229-fold selectivity over human MT1 and Xenopus mel1c receptor subtypes.

物理化学性质&存储条件

分子量 334.46
分子式 C22H26N2O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-pentanoyl-2-benzyltryptamine

参考文献

1. Kojima S, et al. Br J Pharmacol. 2011 Mar;162(5):1179-85.

2. Teh MT, et al. Naunyn Schmiedebergs Arch Pharmacol.

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