MT-031 |CAS:1802158-63-9 Probechem Biochemicals

Chemical Structure : MT-031

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MT-031 (MT 031;MT031)

货号: PC-60449Not For Human Use, Lab Use Only.

A potent, brain penetrant, dual MAO-A and AChE inhibitor that shows neuroprotective effects both in vitro and in vivo.

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生物&药学活性

MT-031 (MT031) is a potent, brain penetrant, dual MAO-A and AChE inhibitor that shows neuroprotective effects both in vitro and in vivo.
MT-031 inhibits H2O2-induced neurotoxicity in human neuroblastoma SH-SY5Y cells, and antagonizes scopolamine-induced memory and cognitive impairments in mice.
MT-031 upregulates mRNA expression levels of Bcl-2, the neurotrophic factors and the anti-inflammatory cytokine, Ntrk, and down-regulates the mRNA expression levels of IL-6 in scopolamine-induced mice.

物理化学性质&存储条件

分子量	274.364
分子式	C16H22N2O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-Ethyl-methyl-carbamic acid 3-[1-(methyl-prop-2-ynyl-amino)-ethyl]-phenyl ester

参考文献

1. Liu W, et al. Neuropharmacology. 2017 Feb;113(Pt A):445-456.

2. Liu W, et al. Neuropharmacology. 2016 Oct;109:376-385.

MT-031 (MT 031;MT031)

生物&药学活性

物理化学性质&存储条件

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MT-031 (MT 031;MT031)

生物&药学活性

物理化学性质&存储条件

参考文献

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