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首页-小分子抑制剂&激动剂-Cell Cycle/DNA Damage-Telomerase-MST-312
MST-312

Chemical Structure : MST-312

CAS No.: 368449-04-1

MST-312 (Telomerase Inhibitor IX, MST312)

货号: PC-63056Not For Human Use, Lab Use Only.

MST-312 (Telomerase Inhibitor IX) is a potent, reversible telomerase inhibitor that effectively reduces telomere length and inhibits proliferation in U937 cells at 1 uM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

MST-312 (Telomerase Inhibitor IX) is a potent, reversible telomerase inhibitor that effectively reduces telomere length and inhibits proliferation in U937 cells at 1 uM.
MST-312 exertes a dose-dependent short-term cytotoxic effect on APL cells, with G2/M cell cycle arrest, and induces apoptosis of APL cells in caspase-mediated manner.
MST-312 also suppresses HSV replication at multiple steps of viral infection.

物理化学性质&存储条件

分子量 380.35
分子式 C20H16N2O6
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N,N'-1,3-Phenylenebis[2,3-dihydroxybenzamide]

参考文献

1. Seimiya H, et al. Cancer Cell. 2005 Jan;7(1):25-37.

2. Fatemi A, et al. Tumour Biol. 2015 Nov;36(11):8425-37.

3. Haberichter J, et al. J Virol. 2015 Oct;89(19):9804-16.

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