MSNBA

Chemical Structure : MSNBA

CAS No.: 852702-51-3

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货号: PC-25569Not For Human Use, Lab Use Only.

MSNBA is a specific inhibitor of glucose transporter GLUT5, competitively inhibits GLUT5 fructose uptake with Ki of 3.2 uM, inhibits GLUT5 fructose transport in proteoliposomes with IC50 of 0.1 uM.

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50 mg	￥380	In stock
100 mg	￥580	In stock
250 mg	￥880	In stock
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生物&药学活性

MSNBA is a specific inhibitor of glucose transporter GLUT5, competitively inhibits GLUT5 fructose uptake with Ki of 3.2 uM, inhibits GLUT5 fructose transport in proteoliposomes with IC50 of 0.1 uM.
MSNBA does not affect the fructose transport of human GLUT2 or the glucose transport of human GLUT1-4 or bacterial GlcPSe.
MSNBA potently inhibitsfructose uptake by GLUT5 in the human breast adenocarcinoma cell line MCF7 (IC50=5.8 uM).

物理化学性质&存储条件

分子量	336.32
分子式	C14H12N2O6S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(4-Methanesulfonyl-2-nitrophenyl)-2H-1,3-benzodioxol-5-amine

参考文献

1. George Thompson AM, et al. Sci Rep. 2016 Apr 14;6:24240.

MSNBA

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MSNBA

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