MSDC-0602 | MPC inhibitor | Probechem Biochemicals

Chemical Structure : MSDC-0602

CAS No.: 1133819-87-0

加入收藏

MSDC-0602 (Azemiglitazone, MSDC0602)

货号: PC-38093Not For Human Use, Lab Use Only.

MSDC-0602 (Azemiglitazone) is a PPARγ-sparing thiazolidinedione insulin sensitizer, targets mitochondrial pyruvate carrier protein (MPC) Mpc1 and Mpc2.

规格	价格	库存
10 mg	￥980	In stock
25 mg	￥1580	In stock
50 mg	￥2580	In stock
100 mg	￥3980	In stock
250 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

MSDC-0602 (Azemiglitazone) is a PPARγ-sparing thiazolidinedione insulin sensitizer, targets mitochondrial pyruvate carrier protein (MPC) Mpc1 and Mpc2.
MSDC-0602 prevented and reversed liver fibrosis and suppressed expression of markers of stellate cell activation in livers of mice fed a diet rich in trans-fatty acids, fructose, and cholesterol.
MSDC-0602 directly reduced hepatic stellate cell activation in vitro.
MSDC-0602 treatment or hepatocyte MPC2 deletion also limited stellate cell activation indirectly by affecting secretion of exosomes from hepatocytes.

物理化学性质&存储条件

分子量	371.4
分子式	C19H17NO5S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	5-(4-(2-(3-Methoxyphenyl)-2-oxoethoxy)benzyl)thiazolidine-2,4-dione

参考文献

1. Colca JR, et al. PLoS One. 2013 May 15;8(5):e61551.

2. Fukunaga T, et al. J Bone Miner Res. 2015 Mar;30(3):481-8.

3. McCommis KS, et al. Hepatology. 2017 May;65(5):1543-1556.

MSDC-0602 (Azemiglitazone, MSDC0602)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

MSDC-0602 (Azemiglitazone, MSDC0602)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.