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首页-小分子抑制剂&激动剂-Cell Cycle/DNA Damage-Nucleoside Antimetabolite/Analog-MSD-914
MSD-914

Chemical Structure : MSD-914

CAS No.:

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MSD-914 (MSD914)

货号: PC-26077Not For Human Use, Lab Use Only.

MSD-914 is a potent, selective S-adenosylhomocysteine hydrolase (AHCY) inhibitor with IC50 of 40 nM, shows broad-spectrum in vitro anti-filovirus activity against EBOV, Marburg virus, and Sudan ebolavirus.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

MSD-914 is a potent, selective S-adenosylhomocysteine hydrolase (AHCY) inhibitor with IC50 of 40 nM, shows broad-spectrum in vitro anti-filovirus activity against EBOV, Marburg virus, and Sudan ebolavirus.

物理化学性质&存储条件

分子量 250.28
分子式 C11H15FN6
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(1R,2R,3R)-3-(4-amino-7-fluoro-1H-imidazo[4,5-c]pyridin-1-yl)cyclopentane-1,2-diamine

参考文献

1. Antonella Converso, et al. Bioorg Med Chem Lett. 2014 Jun 15;24(12):2737-40.

2. Johnston SC, et al. PLoS One. 2026 Feb 6;21(2):e0340118.

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