MS7972 |CAS:352553-42-5 Probechem Biochemicals

Chemical Structure : MS7972

CAS No.: 352553-42-5

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MS7972 (MS-7972)

货号: PC-62280Not For Human Use, Lab Use Only.

MS7972 is a small molecules that blocks p53 and CREB binding protein (CBP) association, completely blocks CBP BRD/p53-AcK382 interactions at 50 uM, results in loss of p53 phosphorylation at Ser15 as well as acetylation at Lys382.

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10 mg	￥2280	In stock
25 mg	￥3880	In stock
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生物&药学活性

MS7972 is a small molecules that blocks p53 and CREB binding protein (CBP) association, completely blocks CBP BRD/p53-AcK382 interactions at 50 uM, results in loss of p53 phosphorylation at Ser15 as well as acetylation at Lys382.
MS7972 causes a dramatic decrease of the doxorubicin-induced p53 increase in U2OS cells.

物理化学性质&存储条件

分子量	227.263
分子式	C14H13NO2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	9-Acetyl-3,4-dihydro-2H-carbazol-1-one

参考文献

1. Sachchidanand, et al. Chem Biol. 2006 Jan;13(1):81-90.

MS7972 (MS-7972)

生物&药学活性

物理化学性质&存储条件

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MS7972 (MS-7972)

生物&药学活性

物理化学性质&存储条件

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