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首页-小分子抑制剂&激动剂-Proteasome/Ubiquitin-Deubiquitinase (DUB)-MS5105
MS5105

Chemical Structure : MS5105

CAS No.:

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MS5105 (MS 5105)

货号: PC-22953Not For Human Use, Lab Use Only.

MS5105 is a small molecule OTUB1-covalent ligand, display improved effectiveness in covalently modifying OTUB1 compared with EN523, is useful for DUBTAC design.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

MS5105 is a small molecule OTUB1-covalent ligand, display improved effectiveness in covalently modifying OTUB1 compared with EN523, is useful for DUBTAC design.

物理化学性质&存储条件

分子量 307.41
分子式 C15H21N3O2S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(E)-4-(4-(dimethylamino)but-2-enoyl)-1-(5-methylthiophen-2-yl)piperazin-2-one

参考文献

1. Jin J, et al. Angew Chem Int Ed Engl. 2024 Aug 16:e202415168.

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