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首页-小分子抑制剂&激动剂-GPCR-Proton-sensing GPCRs-MS48107
MS48107

Chemical Structure : MS48107

CAS No.: 2375070-79-2

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MS48107 (MS 48107)

货号: PC-72990Not For Human Use, Lab Use Only.

MS48107 (MS 48107) is a potent, selective, positive allosteric modulator of G protein-coupled receptor 68 (GPR68, Log(αβ/KB)=6.83).

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10 mg ￥1480 In stock
25 mg ￥2680 In stock
50 mg ￥4280 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

MS48107 (MS 48107) is a potent, selective, positive allosteric modulator of G protein-coupled receptor 68 (GPR68, Log(αβ/KB)=6.83).
MS48107 displays good selectivity against all human GPCRome in PRESTO-Tango screening assays.
MS48107 was bioavailable and brain-penetrant in mice.

物理化学性质&存储条件

分子量 417.444
分子式 C23H20FN5O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(2-(4-Amino-6-((4-phenoxybenzyl)amino)-1,3,5-triazin-2-yl)-3-fluorophenyl)methanol

参考文献

1. Xufen Yu, et al. J Med Chem. 2019 Aug 22;62(16):7557-7574.

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