Chemical Structure : MS436
CAS No.: 1395084-25-9
货号: PC-21330Not For Human Use, Lab Use Only.
MS436 is a potent, selective BRD4 BD1 bromodomain inhibitor with Ki values of 30-50 nM, 10-fold selectivity over the BD2.
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---|---|---|---|
10 mg | ¥1780 | In stock | |
25 mg | ¥2980 | In stock | |
50 mg | ¥4580 | In stock | |
100 mg | Get quote |
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MS436 is a potent, selective BRD4 BD1 bromodomain inhibitor with Ki values of 30-50 nM, 10-fold selectivity over the BD2.
MS436 effectively inhibits BRD4 activity in NF-κB-directed production of nitric oxide and pro-inflammatory cytokine interleukin-6 in murine macrophages.
分子量 | 383.43 | |
分子式 | C18H17N5O3S | |
外观性状 | Solid | |
储存条件 |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
(E)-4-((2-amino-4-hydroxy-5-methylphenyl)diazenyl)-N-(pyridin-2-yl)benzenesulfonamide |
1. Zhang G, et al. J Med Chem. 2013 Nov 27;56(22):9251-64.
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