MS102 | USP2 inhibitor | Probechem Biochemicals

Chemical Structure : MS102

加入收藏

MS102 (MS 102, MS-102)

货号: PC-21519Not For Human Use, Lab Use Only.

MS102 is a small molecule, orally available USP2 inhibitor with IC50 of 5.46 uM, induces transient degradation of ACE2 protein and inhibits ACE2-dependent coronavirus infection.

规格	价格	库存	数量
50 mg		Get quote
100 mg		Get quote
200 mg		Get quote
1 g		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

MS102 is a small molecule, orally available USP2 inhibitor with IC50 of 5.46 uM, induces transient degradation of ACE2 protein and inhibits ACE2-dependent coronavirus infection.
MS102 effectively inhibits ACE2-dependent coronavirus hCoV-NL63 (IC50=0.08 uM), with limited or no activity against the ACE2-independent strain hCoV-OC43.
MS102 demonstrated improved efficacy in blocking the infection of primary human bronchial epithelial (NHBE) cells by the authentic SARS-CoV-2 WT, compared to ML364 (Cat#PC-42288).

物理化学性质&存储条件

分子量	596.44
分子式	C24H17BrF3N3O3S2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(4-(4-bromophenyl)thiazol-2-yl)-2-((4-methylphenyl)sulfonamido)-5-(trifluoromethyl)benzamide

参考文献

1. Dang F, et al. Sci Transl Med. 2023 Dec 6;15(725):eadh7668.

MS102 (MS 102, MS-102)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

MS102 (MS 102, MS-102)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.