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首页-小分子抑制剂&激动剂-Epigenetics-Histone Methyltransferase (HMTase)-MS012
MS012

Chemical Structure : MS012

CAS No.: 2089617-83-2

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MS012 (MS 012)

货号: PC-63136Not For Human Use, Lab Use Only.

MS012 is a potent and selective inhibitor of G9a-Like Protein (GLP) lysine methyltransferase with IC50 of 7 nM, shows >30-fold selectivity for GLP over G9a and other methyltransferases..

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    MS012 is a potent and selective inhibitor of G9a-Like Protein (GLP) lysine methyltransferase with IC50 of 7 nM, shows >30-fold selectivity for GLP over G9a and other methyltransferases.

    物理化学性质&存储条件

    分子量 401.555
    分子式 C22H35N5O2
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    N2-Hexyl-6,7-dimethoxy-N4-(1-methylpiperidin-4-yl)quinazoline2,4-diamine

    参考文献

    1. Xiong Y, et al. J Med Chem. 2017 Mar 9;60(5):1876-1891.

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