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首页-小分子抑制剂&激动剂-GPCR-Adenosine Receptor-MRS7469
MRS7469

Chemical Structure : MRS7469

CAS No.: 2257428-60-5

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MRS7469 (MRS 7469)

货号: PC-21511Not For Human Use, Lab Use Only.

MRS7469 is a potent and selective orthosteric A1 adenosine receptor (A1AR) agonist with Ki of 2.14 nM, >2000-fold selective for A1AR over other adenosine receptors.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

MRS7469 is a potent and selective orthosteric A1 adenosine receptor (A1AR) agonist with Ki of 2.14 nM, >2000-fold selective for A1AR over other adenosine receptors.

物理化学性质&存储条件

分子量 389.46
分子式 C19H27N5O4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(2R,3R,4S,5R)-2-(6-((dicyclobutylmethyl)-amino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol

参考文献

1. Dilip K Tosh, et al. J Med Chem. 2019 Feb 14;62(3):1502-1522.

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