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MRS2485

Chemical Structure : MRS2485

CAS No.: 859724-34-8

MRS2485 (MRS-2485)

货号: PC-62065Not For Human Use, Lab Use Only.

MRS 2485 is a potent, irreversible Aβ42 neurotoxicity inhibitor with ID50 of 500 nM, potently blocks the Aβ calcium channel and protects neurons from Aβ toxicity..

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    MRS 2485 is a potent, irreversible Aβ42 neurotoxicity inhibitor with ID50 of 500 nM, potently blocks the Aβ calcium channel and protects neurons from Aβ toxicity.

    物理化学性质&存储条件

    分子量 420.391
    分子式 C22H30BrNO2
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (S)-1-(8-((2-phenylpropanoyl)oxy)octyl)pyridin-1-ium bromide

    参考文献

    1. Diaz JC, et al. Proc Natl Acad Sci U S A. 2009 Mar 3;106(9):3348-53.

    2. Shafrir Y, et al. Proteins. 2010 Dec;78(16):3473-87.

    3. Tchilibon S, et al. Biochem Pharmacol. 2005 Aug 1;70(3):381-93.

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