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首页-小分子抑制剂&激动剂-GPCR-Adenosine Receptor-MRS1754
MRS1754

Chemical Structure : MRS1754

CAS No.: 264622-58-4

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MRS1754 (MRS 1754, MRS-1754)

货号: PC-22524Not For Human Use, Lab Use Only.

MRS 1754 is a potent, adenosine receptor A2BAR selective antagonist with Ki of 1.97 nM, 205-, 255-, and 289-fold selective for the human A2BARs vs. human A1/A2A/A3 ARs, respectively.

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10 mg ￥1580 In stock
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50 mg ￥4780 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

MRS 1754 is a potent, adenosine receptor A2BAR selective antagonist with Ki of 1.97 nM, 205-, 255-, and 289-fold selective for the human A2BARs vs. human A1/A2A/A3 ARs, respectively.

物理化学性质&存储条件

分子量 486.53
分子式 C26H26N6O4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

8-[4-[((4-cyanophenyl)carbamoylmethyl)oxy]phenyl]-1,3-di(n-propyl) xanthine

参考文献

1. Zizzo MG, et al. Br J Pharmacol. 2006 Aug;148(7):956-63.

2. Jacobson KA. Drug Dev Res. 2001 Jan-Feb;52(1-2):178-186.

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