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首页-小分子抑制剂&激动剂-Tyrosine Kinase-Syk-MRL-SYKi
MRL-SYKi

Chemical Structure : MRL-SYKi

CAS No.: 1312534-69-2

MRL-SYKi

货号: PC-20054Not For Human Use, Lab Use Only.

MRL-SYKi is a potent, selective inhibitor of Syk (Spleen tyrosine kinase) with IC50 of <100 nM, also potently inhibits ZAP70 (24 nM in vitro).

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    MRL-SYKi is a potent, selective inhibitor of Syk (Spleen tyrosine kinase) with IC50 of <100 nM, also potently inhibits ZAP70 (24 nM in vitro).

    物理化学性质&存储条件

    分子量 452.57
    分子式 C24H28N4O3S
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (1S,4R)-4-hydroxy-2,2-dimethyl-4-(5-(3-methyl-5-((4-methylpyrimidin-2-yl)amino)phenyl)thiazol-2-yl)cyclohexane-1-carboxylic acid

    参考文献

    1. Capener JL, et al. bioRxiv [Preprint]. 2024 Jun 13:2024.06.12.598544.

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