MRK-898 | GABA A modulator | Probechem Biochemicals

Chemical Structure : MRK-898

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MRK-898 (MRK898)

货号: PC-21943Not For Human Use, Lab Use Only.

MRK-898 is an orally active GABA(A) receptor modulator, binds to α1, α2, α3 or α5 subunit of GABA(A) receptor with Ki values of 1.2 nM, 1.0 nM, 0.73 nM, and 0.50 nM, respectively.

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生物&药学活性

MRK-898 is an orally active GABA(A) receptor modulator, binds to α1, α2, α3 or α5 subunit of GABA(A) receptor with Ki values of 1.2 nM, 1.0 nM, 0.73 nM, and 0.50 nM, respectively.

物理化学性质&存储条件

分子量	400.31
分子式	C20H9F5N4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	[1,1'-Biphenyl]-2-carbonitrile, 2',4-difluoro-5'-[7-(trifluoromethyl)imidazo[1,2-a]pyrimidin-3-yl]-

参考文献

1. John R Atack, et al. Curr Top Med Chem. 2011;11(9):1176-202.

MRK-898 (MRK898)

生物&药学活性

物理化学性质&存储条件

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MRK-898 (MRK898)

生物&药学活性

物理化学性质&存储条件

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