MRK-067 (TPA123, TP13) | GABAA agonist | Probechem Biochemicals

首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-GABA Receptor-MRK-067

Chemical Structure : MRK-067

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MRK-067 (TPA123, TP-13, MRK067)

货号: PC-28086Not For Human Use, Lab Use Only.

MRK-067 (TPA123, TP13) is a high affinity, partial agonist of α1-, α2-, α3-, and α5-containing GABAA receptors with quivalently high affinity (Ki=0.19-0.41 nM).

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

MRK-067 (TPA123, TP13) is a high affinity, partial agonist of α1-, α2-, α3-, and α5-containing GABAA receptors with quivalently high affinity (Ki=0.19-0.41 nM).

物理化学性质&存储条件

分子量	361.41
分子式	C19H19N7O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	7-Cyclobutyl-6-(2-methyl-2H-1,2,4-triazol-3-ylmethoxy)-3-phenyl-1,2,4-triazolo[4,3-b]pyridazine

参考文献

1. Nancy A Ator, et al. J Pharmacol Exp Ther. 2010 Jan;332(1):4-16.

2. Ciara McCabe, et al. Neuropharmacology. 2004 Feb;46(2):171-8.

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MRK-067 (TPA123, TP-13, MRK067)

生物&药学活性

物理化学性质&存储条件

参考文献

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MRK-067 (TPA123, TP-13, MRK067)

生物&药学活性

物理化学性质&存储条件

参考文献

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