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首页-小分子抑制剂&激动剂-GPCR-Mas-related G protein-coupled receptor (MRGPR)-MRGPRX1 agonist 1
MRGPRX1 agonist 1

Chemical Structure : MRGPRX1 agonist 1

CAS No.: 2377379-39-8

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MRGPRX1 agonist 1

货号: PC-38066Not For Human Use, Lab Use Only.

MRGPRX1 agonist 1 is a highly potent MRGPRX1 agonist with EC50 of 50 nM, superior selectivity over opioid receptors.

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5 mg ￥2280 In stock
10 mg ￥3580 In stock
25 mg ￥5480 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

MRGPRX1 agonist 1 is a highly potent MRGPRX1 agonist with EC50 of 50 nM, superior selectivity over opioid receptors.
MRGPRX1 agonist 1 displays favorable distribution to the spinal cord, the presumed site of action for the MRGPRX1-mediated analgesic effects.

物理化学性质&存储条件

分子量 435.498
分子式 C23H21N3O4S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-(2-(1-aminoisoquinolin-6-yloxy)-4-methylphenyl)-2-methoxybenzenesulfonamide

参考文献

1. Prchalová E, et al. J Med Chem. 2019 Sep 26;62(18):8631-8641.

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